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postado por www.rocasdovouga.com.brMiles de mujeres con cáncer de mama avanzado en Inglaterra y Gales son privadas de un medicamento que reduce el 🧾 riesgo de que la enfermedad se propague en más de un tercio
Enhertu ha sido implementado para pacientes con cáncer de 🧾 mama HER2-bajo en Escocia y Irlanda del Norte, pero el Instituto Nacional para la Excelencia en el Cuidado de la 🧾 Salud y la Bienestar (Nice) lo ha rechazado para pacientes en Inglaterra. Las mujeres en Gales también están siendo privadas 🧾 del medicamento.
Evidencia convincente sugiere que el tratamiento, también conocido como trastuzumab deruxtecan, puede aumentar la cantidad de tiempo que viven 🧾 los pacientes y darles más tiempo antes de que su enfermedad avance.
Ahora "datos realmente emocionantes" publicados en la conferencia mundial 🧾 más grande sobre cáncer sugieren que Enhertu es aún más potente de lo que se pensaba previamente.
Los resultados del estudio 🧾 Destiny-Breast06, presentados en la reunión anual de la Sociedad Americana de Oncología Clínica (Asco) en Chicago, muestran que el fármaco 🧾 puede retrasar el crecimiento de los tumores en más de un año, significativamente más tiempo que la quimioterapia estándar.
En general, 🧾 Enhertu redujo el riesgo de crecimiento o propagación del cáncer en pacientes con cáncer de mama HER2-bajo en un 38% 🧾 en comparación con aquellos que recibieron quimioterapia. Los datos aumentarán la presión sobre los reguladores para que aprueben el medicamento 🧾 para mujeres en Inglaterra y Gales.
Las organizaciones benéficas advirtieron que las vidas de las mujeres "se acortarán" con más retrasos 🧾 mientras exhortaban a que Enhertu esté disponible para mujeres en Inglaterra y Gales lo más rápido posible.
Tabla de comparación de 🧾 Enhertu y quimioterapia
| Tratamiento | Reducción del riesgo de crecimiento o propagación del cáncer | Tiempo de control de la enfermedad |
|---|---|---|
| Enhertu | 38% | 13.2 meses |
| Quimioterapia | 0% (línea de base) | 8.1 🧾 meses |
Dr Simon Vincent, director de investigación, apoyo e influencia en el Cáncer de Mama Ahora, dijo: "Este estudio prometedor sugiere 🧾 que aún más personas podrían beneficiarse de Enhertu, ofreciendo a los pacientes con cáncer de mama HER2-bajo o HER2-ultrabajo secundario 🧾 que ya han tenido terapia hormonal más tiempo para vivir sin que su cáncer se propague.
"Esto se suma a la 🧾 evidencia existente de que este tratamiento puede aumentar la supervivencia general en más de seis meses para las personas con 🧾 cáncer de mama HER2-bajo secundario que ya han tenido quimioterapia.
"Sin embargo, a pesar de estos datos clínicos emergentes que sugieren 🧾 claramente los beneficios que Enhertu podría brindar a los pacientes, miles de personas con cáncer de mama HER2-bajo secundario son
The Best Corner Betting Strategy
Corner betting tends to be one of the most misunderstood betting markets. For the vast majority 🧾 of punters, the number of corners is not so stable to predict the winner or the total number of goals 🧾 in a match, so they demoted the market to the “fun bet” level.
In other words, they believe that the number 🧾 of corners is so random that it has little to do with searching and analyzing to be considered a fertile 🧾 field for serious betting. That’s totally wrong. In fact, race to corners meaning is absolutely useful for bettors who are 🧾 interested in betting markets to invest in order to gain long-term profit. And there are two main reasons for this:
Corner 🧾 betting odds are derived mainly by numbers (totals, average etc.) and scratch out their personal percept about the outcome. So, 🧾 it’s easier for a smart punter to “disagree” with raw numbers and find a lot of valuable bets.
The money placed 🧾 on corner bets stands for a tiny percentage of the total money. Thus, bookmakers don’t pay so much attention to 🧾 “correct” the odds, as they don’t feel they are in danger of losing a fortune. Even the greater sums on 🧾 corner betting are not detected easily by the “bet radars”.
How To Predict Corners In Football
It’s true that the vast majority 🧾 of punters place live bets when it comes to corners. But still, you can choose the most profitable corner betting 🧾 strategy when choosing to bet pre-match. These are the best two:
First half corners
Usually, even the best bookmakers for football don’t 🧾 pay much attention to first-half lines. They count an over/under market line for the whole match (i.e. over/under 9,5 corners) 🧾 and divide it into two, subtracting one corner most of the time (i.e. over/under 4,5 corners). Supposing that in several 🧾 leagues (like the Dutch Eredivisie or the German Bundesliga), there’s an ascending number of corners even from the first minutes, 🧾 it’s really worth betting on the over 4,5 corners before halftime.
Wrong lines on specific teams
This corner betting strategy focuses on 🧾 the teams rather than the matches. You have to pick some teams, usually the favorites in every league, who are 🧾 desperate to win every match, especially at home. Then you focus on their attitude: They don’t have to be tired 🧾 after a midweek international or important domestic cup tie.
They have to be fully focused on getting maximum points in the 🧾 game (even better when they’ve lost points at their previous match). So, you’re just sure they’re giving 100% potential during 🧾 most of the 90 minutes, not just to secure victory but to score as many goals as possible.
Most Profitable In-play 🧾 Corner Betting Strategy
Maybe the top in-play corner betting strategy after 85 minutes is taking the Asian over 1 corner. With 🧾 this bet, you get your money back if just one corner is given away, and you win after two or 🧾 more corners. Watch out for games where one team (the favorite) is pushing for a late winner or a late 🧾 equalizer. Odds for this bet start from 1.80-1.90 in 85 min. and ascending as time passes.
A variable of this in-play 🧾 corner betting strategy is on the over 0,5 corners at the dying moments of a match. This bet is open 🧾 for 1-2 minutes only, usually after 88 min. and is still alive during the injury time. But most bookmakers don’t 🧾 leave it open till the end. You can find it at around 1.80-1.90 odds.
When there are many corners in the 🧾 first half; usually bookmakers at least double the exact number to set the line for the whole match. For example, 🧾 when there are 7 corners till halftime, the over/under line will stand at least 14,5 corner kicks. Taking the under 🧾 is, by default, a valuable choice, depending, of course, on the current score.
Another profitable pattern among the best football betting 🧾 strategies is insisting on the starting line. When the pre-match over/under corners line is 10,5, and till halftime, there are 🧾 only three corners marked, the odds on the over 9,5 corners are boosted and are really worthy to take. Given 🧾 the fact, of course, that the match is still claimed by both teams.
When at halftime, there’s a clear score (2-0, 🧾 3-0) for the favorite, taking the under line is the most logical scenario. Especially if the over/under line is, as 🧾 always, doubling the number of corners of the first half. For example, if there are four corners in the first 🧾 half and the over/under line is 9,5 kicks, value hides to the under choice, supposing that the favorite team will 🧾 not push the match to the limit.
Corner kicks in specific leagues
1 Italian Serie A doesn’t seem like a league you 🧾 can win at corner betting. Most of the teams are focused on the defence to grab a valuable result and 🧾 even the powerhouse teams don’t attack when they reach a comfortable score.
2 On the contrary, some attacking-minded leagues as the 🧾 German Bundesliga or the Dutch Eredivisie, have more corners per match, as the teams tend to score more goals and 🧾 keep on attacking till the end, regardless of the current score.
3 Latin American Leagues , especially Brazil and Colombia, have 🧾 many more corners than European leagues due to talented lateral strikers.
4 Watch for over lines in African Championships (especially South 🧾 Africa) or international competitions in Africa for clubs and national teams. In general, African goalkeepers are less stable than their 🧾 European counterparts.
5 Many Eastern European leagues tend to have fewer corners than Western European ones. The match tempo is much 🧾 slower than in Western Europe, there aren’t so many shots on goal, especially during the winter months.
Also Read: UEFA Conference 🧾 League Betting Tips
How To Bet On Corners And Win
The goalkeepers' ability to block the ball under every circumstance or punch 🧾 it away is a crucial factor for the total number of corners. In order to win at corner betting, watch 🧾 their attitude during the match when it comes to long passes, volleys or fierce shots. Watch what they do during 🧾 a corner kick, do they go aggressively to the ball or wait stacked at their goal line?
⏩ Central defenders: Gifted 🧾 players, who are tall and strong enough to win all body challenges in the box, but can also pass and 🧾 dribble accurately, are rare in modern football. Watch for less-skilled players who have in mind primarily to drive away the 🧾 ball at any cost. They’re going to allow much more corner kicks during a match.
⏩ Bad Weather (rain, snow etc.): 🧾 There’s some contradiction about whether heavy rain or snow could be a sign for more or less corners. Some insist 🧾 that due to the slippery terrain, goalkeepers and defenders don’t think twice before giving a corner, to prevent worse situations 🧾 for their team. Others claim that due to this fear (and given that offensive players have the same difficulty to 🧾 create chances), they become extremely careful not to allow many set pieces around their goal. I support the first version.
⏩ 🧾 Injuries/suspensions: Watch out for specific absences, which can affect crucially the average number of corners a team has in a 🧾 match. A change of the starting goalkeeper, a fast striker who likes to play on the line and usually invades 🧾 the box, or a smart midfielder capable of making accurate lateral passes are important factors in a match.
⏩ Allegations of 🧾 “fixed” results: I usually avoid even mentioning “fixed” matches, but let’s face it. In some leagues, this is a reality. 🧾 You might have heard that the exact number of corner kicks is easier to be fixed than the final result 🧾 or the number of goals, as this number does not affect crucially any win/lose scenario. Unfortunately, you’ll bump into some 🧾 unknown “friends” eager to provide you with information about “free money” from corner kicks, I strongly advise you to avoid 🧾 them. But if you’re watching a football match and you observe a suspicious urge of defenders to give away corners, 🧾 don’t hesitate to bet. After all, it’s your decision.
⏩ Shots per game: Do you want to learn how to bet 🧾 on football and win? This is a number found on many statistics websites, mainly from the top leagues. The bigger 🧾 the number of shots per game, the greater the chance of getting more corner kicks. Look for the team who’s 🧾 away from the average numbers, bookmakers still pay more attention to the league’s average number to offer odds.
Can you win 🧾 at a corner kick betting?
As you can see, there are many ways to make a profit through corner betting. This 🧾 betting market doesn’t depend on luck but on betting discipline, accuracy, analysis and momentum. There are specific teams who count 🧾 mainly on set pieces to score, others with excellent sideline strikers, and leagues which produce a lot of corners. All 🧾 you have to do is analyze and place your bets.
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The Best Corner Betting Strategy
Corner betting tends to be one of the most misunderstood betting markets. For the vast majority 🧾 of punters, the number of corners is not so stable to predict the winner or the total number of goals 🧾 in a match, so they demoted the market to the “fun bet” level.
In other words, they believe that the number 🧾 of corners is so random that it has little to do with searching and analyzing to be considered a fertile 🧾 field for serious betting. That’s totally wrong. In fact, race to corners meaning is absolutely useful for bettors who are 🧾 interested in betting markets to invest in order to gain long-term profit. And there are two main reasons for this:
Corner 🧾 betting odds are derived mainly by numbers (totals, average etc.) and scratch out their personal percept about the outcome. So, 🧾 it’s easier for a smart punter to “disagree” with raw numbers and find a lot of valuable bets.
The money placed 🧾 on corner bets stands for a tiny percentage of the total money. Thus, bookmakers don’t pay so much attention to 🧾 “correct” the odds, as they don’t feel they are in danger of losing a fortune. Even the greater sums on 🧾 corner betting are not detected easily by the “bet radars”.
How To Predict Corners In Football
It’s true that the vast majority 🧾 of punters place live bets when it comes to corners. But still, you can choose the most profitable corner betting 🧾 strategy when choosing to bet pre-match. These are the best two:
First half corners
Usually, even the best bookmakers for football don’t 🧾 pay much attention to first-half lines. They count an over/under market line for the whole match (i.e. over/under 9,5 corners) 🧾 and divide it into two, subtracting one corner most of the time (i.e. over/under 4,5 corners). Supposing that in several 🧾 leagues (like the Dutch Eredivisie or the German Bundesliga), there’s an ascending number of corners even from the first minutes, 🧾 it’s really worth betting on the over 4,5 corners before halftime.
Wrong lines on specific teams
This corner betting strategy focuses on 🧾 the teams rather than the matches. You have to pick some teams, usually the favorites in every league, who are 🧾 desperate to win every match, especially at home. Then you focus on their attitude: They don’t have to be tired 🧾 after a midweek international or important domestic cup tie.
They have to be fully focused on getting maximum points in the 🧾 game (even better when they’ve lost points at their previous match). So, you’re just sure they’re giving 100% potential during 🧾 most of the 90 minutes, not just to secure victory but to score as many goals as possible.
Most Profitable In-play 🧾 Corner Betting Strategy
Maybe the top in-play corner betting strategy after 85 minutes is taking the Asian over 1 corner. With 🧾 this bet, you get your money back if just one corner is given away, and you win after two or 🧾 more corners. Watch out for games where one team (the favorite) is pushing for a late winner or a late 🧾 equalizer. Odds for this bet start from 1.80-1.90 in 85 min. and ascending as time passes.
A variable of this in-play 🧾 corner betting strategy is on the over 0,5 corners at the dying moments of a match. This bet is open 🧾 for 1-2 minutes only, usually after 88 min. and is still alive during the injury time. But most bookmakers don’t 🧾 leave it open till the end. You can find it at around 1.80-1.90 odds.
When there are many corners in the 🧾 first half; usually bookmakers at least double the exact number to set the line for the whole match. For example, 🧾 when there are 7 corners till halftime, the over/under line will stand at least 14,5 corner kicks. Taking the under 🧾 is, by default, a valuable choice, depending, of course, on the current score.
Another profitable pattern among the best football betting 🧾 strategies is insisting on the starting line. When the pre-match over/under corners line is 10,5, and till halftime, there are 🧾 only three corners marked, the odds on the over 9,5 corners are boosted and are really worthy to take. Given 🧾 the fact, of course, that the match is still claimed by both teams.
When at halftime, there’s a clear score (2-0, 🧾 3-0) for the favorite, taking the under line is the most logical scenario. Especially if the over/under line is, as 🧾 always, doubling the number of corners of the first half. For example, if there are four corners in the first 🧾 half and the over/under line is 9,5 kicks, value hides to the under choice, supposing that the favorite team will 🧾 not push the match to the limit.
Corner kicks in specific leagues
1 Italian Serie A doesn’t seem like a league you 🧾 can win at corner betting. Most of the teams are focused on the defence to grab a valuable result and 🧾 even the powerhouse teams don’t attack when they reach a comfortable score.
2 On the contrary, some attacking-minded leagues as the 🧾 German Bundesliga or the Dutch Eredivisie, have more corners per match, as the teams tend to score more goals and 🧾 keep on attacking till the end, regardless of the current score.
3 Latin American Leagues , especially Brazil and Colombia, have 🧾 many more corners than European leagues due to talented lateral strikers.
4 Watch for over lines in African Championships (especially South 🧾 Africa) or international competitions in Africa for clubs and national teams. In general, African goalkeepers are less stable than their 🧾 European counterparts.
5 Many Eastern European leagues tend to have fewer corners than Western European ones. The match tempo is much 🧾 slower than in Western Europe, there aren’t so many shots on goal, especially during the winter months.
Also Read: UEFA Conference 🧾 League Betting Tips
How To Bet On Corners And Win
The goalkeepers' ability to block the ball under every circumstance or punch 🧾 it away is a crucial factor for the total number of corners. In order to win at corner betting, watch 🧾 their attitude during the match when it comes to long passes, volleys or fierce shots. Watch what they do during 🧾 a corner kick, do they go aggressively to the ball or wait stacked at their goal line?
⏩ Central defenders: Gifted 🧾 players, who are tall and strong enough to win all body challenges in the box, but can also pass and 🧾 dribble accurately, are rare in modern football. Watch for less-skilled players who have in mind primarily to drive away the 🧾 ball at any cost. They’re going to allow much more corner kicks during a match.
⏩ Bad Weather (rain, snow etc.): 🧾 There’s some contradiction about whether heavy rain or snow could be a sign for more or less corners. Some insist 🧾 that due to the slippery terrain, goalkeepers and defenders don’t think twice before giving a corner, to prevent worse situations 🧾 for their team. Others claim that due to this fear (and given that offensive players have the same difficulty to 🧾 create chances), they become extremely careful not to allow many set pieces around their goal. I support the first version.
⏩ 🧾 Injuries/suspensions: Watch out for specific absences, which can affect crucially the average number of corners a team has in a 🧾 match. A change of the starting goalkeeper, a fast striker who likes to play on the line and usually invades 🧾 the box, or a smart midfielder capable of making accurate lateral passes are important factors in a match.
⏩ Allegations of 🧾 “fixed” results: I usually avoid even mentioning “fixed” matches, but let’s face it. In some leagues, this is a reality. 🧾 You might have heard that the exact number of corner kicks is easier to be fixed than the final result 🧾 or the number of goals, as this number does not affect crucially any win/lose scenario. Unfortunately, you’ll bump into some 🧾 unknown “friends” eager to provide you with information about “free money” from corner kicks, I strongly advise you to avoid 🧾 them. But if you’re watching a football match and you observe a suspicious urge of defenders to give away corners, 🧾 don’t hesitate to bet. After all, it’s your decision.
⏩ Shots per game: Do you want to learn how to bet 🧾 on football and win? This is a number found on many statistics websites, mainly from the top leagues. The bigger 🧾 the number of shots per game, the greater the chance of getting more corner kicks. Look for the team who’s 🧾 away from the average numbers, bookmakers still pay more attention to the league’s average number to offer odds.
Can you win 🧾 at a corner kick betting?
As you can see, there are many ways to make a profit through corner betting. This 🧾 betting market doesn’t depend on luck but on betting discipline, accuracy, analysis and momentum. There are specific teams who count 🧾 mainly on set pieces to score, others with excellent sideline strikers, and leagues which produce a lot of corners. All 🧾 you have to do is analyze and place your bets.
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